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Analysis of associations between multiple causes of death using methods of network analysis
Ukolova, Elizaveta ; Burcin, Boris (advisor) ; Lustigová, Michala (referee)
The aim of the thesis is the application of network analysis methods in the study of relationships between multiple causes of death. As a result of increasing life expectancy and of the growing proportion of people dying from chronic diseases in developed countries, the analysis of multiple causes of death may be a relevant topic, as this approach makes it possible to analyse the circumstances of dying, not just the single cause initiating the entire disease chain leading to death. The purpose of this work is to construct the system of causes of death, in which the complexity of the relationships between the causes of death reported on the death certificate would be captured. First network is created from the first part of the death certificate, and we distinguish between the "causing" condition and the consequent one in a pair of multiple causes of death. The second network is designed for the second part of the death certificate, and in this network, we do not differentiate the direction of the link. Networks are then analysed with various centrality measures and community detection, and we also examine neighbours of selected diseases. Essential part of the thesis is the explanatory analysis of multiple causes of death, because it determines methods later used in network analysis. It was found...
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